Plant Biology Department,
Nano Research Area
- Health & Bio-Nanotechnology
I am Director of the Cellular and Molecular Imaging Facility (CMIF) located in the Plant Biology Department at NC State. This facility houses a number of microscopes, including a Leica confocal laser scanning microscope and Video microscopes, and its users come from five colleges in the university. The Associate Director, Dr. Eva Johannes, is available to instruct and help users get the best images possible.
We have a long-standing interest in further improving methods of digitally enhanced light microscopy. We have developed a new method, Polarization Modulation DIC, and we will continue to further test and develop the polarization modulation microscope as well as any other microscope improvements we find necessary in order to record dynamic events in living cells. I study the cytoskeleton and signal transduction. These filaments range from 2 nm to 25 nm in diameter. We also have a biocurrents probe and measure currents around cells with great accuracy.
More recently, we have become interested in developing biosensors in collaboration with professors in Engineering and Physics at NC State. The eventual goal is to develop very small sensors that can be placed next to or in cells to measure a number of parameters.